Dr Fitzclarence is a Rural Generalist and has worked rurally for the majority of her career. She has worked in the Northern Territory including for the Aerial Medical Service; Rural South Australia; the Kimberley; and the Pilbara. She has worked for in government health services, Aboriginal Health Services and privately. Her specific interests include lifestyle medicine, renal medicine, chronic disease, prison health and medical education.

Dr Fitzclarence is extensively involved with the rural clinical school and is an examiner for ACRRM.